Omicron’s message on vaccines: Boosting begets breadth

Contributing Author:

Cell. 2022 Feb 3;185(3):411-413. doi: 10.1016/j.cell.2022.01.006. Epub 2022 Jan 14.


In this issue of Cell, three studies confirm that SARS-CoV-2 Omicron strongly evades a key immune defense-neutralizing antibodies. However, while one- or two-dose vaccine regimens fail to induce anti-Omicron neutralizing antibodies, a homologous third-dose booster rescues neutralization function in a way that highlights the adaptability of immune memory, where recalled immunity extends antibody reach across SARS-CoV-2 variants.

PMID:35065712 | PMC:PMC8758338 | DOI:10.1016/j.cell.2022.01.006