Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses
Science. 2023 Apr 7;380(6640):eadc9498. doi: 10.1126/science.adc9498. Epub 2023 Apr 7. ABSTRACT Despite the vast diversity of the antibody repertoire, infected individuals often mount antibody responses
Novel Treatments for Airway Disease
N Engl J Med. 2017 Aug 10;377(6):597. doi: 10.1056/NEJMc1708004. NO ABSTRACT PMID:28813135 | DOI:10.1056/NEJMc1708004
Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity
J Exp Med. 2024 Oct 7;221(10):e20231193. doi: 10.1084/jem.20231193. Epub 2024 Sep 25. ABSTRACT Upon antigenic stimulation, naïve CD4+ T cells can give rise to phenotypically
High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance
Commun Med (Lond). 2024 Jul 2;4(1):128. doi: 10.1038/s43856-024-00525-8. ABSTRACT BACKGROUND: Human carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) is an inhibitory cell surface protein that
Linear RAG scanning mediates editing of Igκ variable region repertoires
Nature. 2026 Apr 15. doi: 10.1038/s41586-026-10362-5. Online ahead of print. ABSTRACT V(D)J recombination-mediated Igκ light chain variable region exon assembly in precursor (pre)-B cells involves
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct