Genetic regulation of OAS1 nonsense-mediated decay underlies association with risk of severe COVID-19
medRxiv. 2021 Jul 13:2021.07.09.21260221. doi: 10.1101/2021.07.09.21260221. Preprint. ABSTRACT Genomic regions have been associated with COVID-19 susceptibility and outcomes, including the chr12q24.13 locus encoding antiviral proteins
Immune recall improves antibody durability and breadth to SARS-CoV-2 variants
Sci Immunol. 2022 May 12:eabp8328. doi: 10.1126/sciimmunol.abp8328. Online ahead of print. ABSTRACT Key features of immune memory are greater and faster antigen-specific antibody responses to
Immunology of allergen immunotherapy
Immunother Adv. 2022 Nov 25;2(1):ltac022. doi: 10.1093/immadv/ltac022. eCollection 2022. NO ABSTRACT PMID:36530352 | PMC:PMC9749131 | DOI:10.1093/immadv/ltac022
The purinergic G protein-coupled receptor 6 inhibits effector T cell activation in allergic pulmonary inflammation
J Immunol. 2011 Aug 1;187(3):1486-95. doi: 10.4049/jimmunol.1003669. Epub 2011 Jul 1. ABSTRACT We show that the P2Y(6) receptor, a purinergic G protein-coupled receptor with a
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants
Science. 2021 Aug 6;373(6555):642-648. doi: 10.1126/science.abi9745. Epub 2021 Jun 24. ABSTRACT Several fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have become the