Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions
J Immunol. 2014 Mar 15;192(6):2812-20. doi: 10.4049/jimmunol.1301794. Epub 2014 Feb 12. ABSTRACT We previously established a mast cell (MC)-dependent thermal injury model in mice with
The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch
Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2022087118. doi: 10.1073/pnas.2022087118. ABSTRACT Acute and chronic itch are burdensome manifestations of skin pathologies including allergic
Addicted to green: priming effect of menthol cigarette packaging on brain response to smoking cues
Tob Control. 2021 Oct 1:tobaccocontrol-2021-056639. doi: 10.1136/tobaccocontrol-2021-056639. Online ahead of print. ABSTRACT INTRODUCTION: Mentholated tobacco cigarettes are believed to be more addictive than non-menthol ones.
Immune recall improves antibody durability and breadth to SARS-CoV-2 variants
Sci Immunol. 2022 May 12:eabp8328. doi: 10.1126/sciimmunol.abp8328. Online ahead of print. ABSTRACT Key features of immune memory are greater and faster antigen-specific antibody responses to
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike
Cell. 2021 Sep 16;184(19):4969-4980.e15. doi: 10.1016/j.cell.2021.07.025. Epub 2021 Jul 23. ABSTRACT Memory B cell reserves can generate protective antibodies against repeated SARS-CoV-2 infections, but with