Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,
Improving radiologist’s ability in identifying particular abnormal lesions on mammograms through training test set with immediate feedback
Sci Rep. 2021 May 10;11(1):9899. doi: 10.1038/s41598-021-89214-3. ABSTRACT It has been shown that there are differences in diagnostic accuracy of cancer detection on mammograms, from
Updating the classification and routine diagnosis of NSAID hypersensitivity reactions: A WAO Statement
World Allergy Organ J. 2025 Aug 12;18(8):101086. doi: 10.1016/j.waojou.2025.101086. eCollection 2025 Aug. ABSTRACT Hypersensitivity reactions to non-steroidal anti-inflammatory drugs (NSAIDs) have been classified as immediate
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6
J Immunol. 2013 Feb 15;190(4):1758-66. doi: 10.4049/jimmunol.1202567. Epub 2013 Jan 14. ABSTRACT Mast cells (MC) and basophils share expression of the high-affinity receptor for IgE
Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant
Science. 2021 Dec 10;374(6573):1353-1360. doi: 10.1126/science.abl9463. Epub 2021 Oct 26. ABSTRACT The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has outcompeted previously