Immune recall improves antibody durability and breadth to SARS-CoV-2 variants
Sci Immunol. 2022 May 12:eabp8328. doi: 10.1126/sciimmunol.abp8328. Online ahead of print. ABSTRACT Key features of immune memory are greater and faster antigen-specific antibody responses to
DNA vaccine protection against SARS-CoV-2 in rhesus macaques
Science. 2020 Aug 14;369(6505):806-811. doi: 10.1126/science.abc6284. Epub 2020 May 20. ABSTRACT The global coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus
Airway brush cells generate cysteinyl leukotrienes through the ATP sensor P2Y2
Sci Immunol. 2020 Jan 17;5(43):eaax7224. doi: 10.1126/sciimmunol.aax7224. Epub 2020 Jan 17. ABSTRACT Chemosensory epithelial cells (EpCs) are specialized cells that promote innate type 2 immunity
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
30-Year Review of Pediatric- and Adult-Onset CVID: Clinical Correlates and Prognostic Indicators
J Clin Immunol. 2019 Oct;39(7):678-687. doi: 10.1007/s10875-019-00674-9. Epub 2019 Aug 3. ABSTRACT PURPOSE: To evaluate mortality risk factors in pediatric-onset common variable immunodeficiency disorders (CVID),
Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity
J Exp Med. 2024 Oct 7;221(10):e20231193. doi: 10.1084/jem.20231193. Epub 2024 Sep 25. ABSTRACT Upon antigenic stimulation, naïve CD4+ T cells can give rise to phenotypically
