First-Dose mRNA COVID-19 Vaccine Allergic Reactions: Limited Role for Excipient Skin Testing
J Allergy Clin Immunol Pract. 2021 Sep;9(9):3308-3320.e3. doi: 10.1016/j.jaip.2021.06.010. Epub 2021 Jun 22. ABSTRACT BACKGROUND: The Centers for Disease Control and Prevention state that a
High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform
Nat Biotechnol. 2023 Jan 2. doi: 10.1038/s41587-022-01566-x. Online ahead of print. ABSTRACT Identification of CD8+ T cell epitopes is critical for the development of immunotherapeutics.
One Allergy, Two Paths: Navigating Penicillin Evaluation in Pregnant Patients Direct Challenges vs Penicillin Skin Testing in Pregnancy: A Controversies in Allergy Review
J Allergy Clin Immunol Pract. 2025 Nov 28:S2213-2198(25)01135-3. doi: 10.1016/j.jaip.2025.11.030. Online ahead of print. ABSTRACT Unverified penicillin allergy labels are common and can result in
Multi-omic analysis reveals a key BCAT1 role in mTOR activation by B-cell receptor and TLR9
J Clin Invest. 2025 Sep 9:e186258. doi: 10.1172/JCI186258. Online ahead of print. ABSTRACT B-lymphocytes play major adaptive immune roles, producing antibody and driving T-cell responses.
Global processing provides malignancy evidence complementary to the information captured by humans or machines following detailed mammogram inspection
Sci Rep. 2021 Oct 11;11(1):20122. doi: 10.1038/s41598-021-99582-5. ABSTRACT The information captured by the gist signal, which refers to radiologists’ first impression arising from an initial
Antibody-mediated SARS-CoV-2 entry in cultured cells
EMBO Rep. 2023 Dec 6;24(12):e57724. doi: 10.15252/embr.202357724. Epub 2023 Nov 2. ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters host cells by first engaging