Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma
J Immunol. 2014 Nov 15;193(10):4783-4789. doi: 10.4049/jimmunol.1302947. Epub 2014 Oct 15. ABSTRACT Allergic asthma is a complex disease with a strong genetic component where mast
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,
Analysis of anticholinergic adverse effects using two large databases: The US Food and Drug Administration Adverse Event Reporting System database and the Japanese Adverse Drug Event Report database
PLoS One. 2021 Dec 2;16(12):e0260980. doi: 10.1371/journal.pone.0260980. eCollection 2021. ABSTRACT INTRODUCTION: Anticholinergic adverse effects (AEs) are a problem for elderly people. This study aimed to
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
Cell. 2020 May 28;181(5):1016-1035.e19. doi: 10.1016/j.cell.2020.04.035. Epub 2020 Apr 27. ABSTRACT There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome
Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99
Proc Natl Acad Sci U S A. 2016 May 31;113(22):6242-7. doi: 10.1073/pnas.1605957113. Epub 2016 May 16. ABSTRACT Cysteinyl leukotrienes (cysLTs), leukotriene C4 (LTC4), LTD4, and
Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant
Science. 2021 Dec 10;374(6573):1353-1360. doi: 10.1126/science.abl9463. Epub 2021 Oct 26. ABSTRACT The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has outcompeted previously
