Research within the Vinik Center spans from basic immunobiology to disease pathogenesis and population health, and includes an emphasis in the following areas:

immune function of lipid mediators

innate immunity and inflammation

lymphocyte biology


mast cell biology

immunoglobulin generation and signaling

microbiome research and immunocyte development

genomics and metabolomics of asthma and chronic inflammatory disease

clinical trials in asthma, aspirin-exacerbated respiratory disease, chronic sinusitis

clinical trials in mast cell disorders

population studies in asthma, food allergy, and drug allergy

Select Publications

Immune recall improves antibody durability and breadth to SARS-CoV-2 variants

Yuezhou Chen, et al.  Sci Immunol. 2022 

Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling

Xin Wang, et al. bioRixiv 2022

Comparative efficacy of tezepelumab to mepolizumab, benralizumab, and dupilumab in eosinophilic asthma: A Bayesian network meta-analysis

Ayobami Akenroye , et al. JACI 2022

Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation

Daniel Dwyer, Sci Immunol. 2021

Maintaining Safety with SARS-CoV-2 Vaccines

Mariana Castells, New England Journal of Medicine 2021

Asthma Exacerbations in Patients with Type 2 Diabetes and Asthma on Glucagon-like Peptide-1 Receptor Agonists

Dinah Foer, Am J Respir Crit Care Med 2021

Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production

Yuezhou Chen, Cell 2020

IL-5Rα marks nasal polyp IgG4- and IgE-expressing cells in AERD

Kathleen Buchheit, J Allergy Clin Immunol 2020

Airway brush cells generate cysteinyl leukotrienes through the ATP sensor P2Y2

Saltanat Ualiyeva, Sci Immunol. 2020

Additional Information