Disparities in United States hospitalizations for serious infections in patients with and without opioid use disorder: A nationwide observational study
PLoS Med. 2020 Aug 7;17(8):e1003247. doi: 10.1371/journal.pmed.1003247. eCollection 2020 Aug. ABSTRACT BACKGROUND: Patients with opioid use disorder (OUD) who are hospitalized for serious infections requiring
Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant
Science. 2021 Dec 10;374(6573):1353-1360. doi: 10.1126/science.abl9463. Epub 2021 Oct 26. ABSTRACT The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has outcompeted previously
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
Machine learning approaches reveal genomic regions associated with sugarcane brown rust resistance
Sci Rep. 2020 Nov 18;10(1):20057. doi: 10.1038/s41598-020-77063-5. ABSTRACT Sugarcane is an economically important crop, but its genomic complexity has hindered advances in molecular approaches for
Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6
J Immunol. 2013 Feb 15;190(4):1758-66. doi: 10.4049/jimmunol.1202567. Epub 2013 Jan 14. ABSTRACT Mast cells (MC) and basophils share expression of the high-affinity receptor for IgE
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
Cell. 2022 Feb 2:S0092-8674(22)00067-8. doi: 10.1016/j.cell.2022.01.009. Online ahead of print. ABSTRACT Activation of the innate immune system via pattern recognition receptors (PRRs) is key to