Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,
Whence and wherefore IgE?
Immunol Rev. 2024 Jul 23. doi: 10.1111/imr.13373. Online ahead of print. ABSTRACT Despite the near ubiquitous presence of Ig-based antibodies in vertebrates, IgE is unique
Trends in pharmacologic treatment of chronic idiopathic urticaria from 2016 to 2020
Ann Allergy Asthma Immunol. 2022 May;128(5):602-603. doi: 10.1016/j.anai.2022.02.006. Epub 2022 Feb 25. NO ABSTRACT PMID:35227905 | PMC:PMC9058201 | DOI:10.1016/j.anai.2022.02.006
Genetic regulation of OAS1 nonsense-mediated decay underlies association with risk of severe COVID-19
medRxiv. 2021 Jul 13:2021.07.09.21260221. doi: 10.1101/2021.07.09.21260221. Preprint. ABSTRACT Genomic regions have been associated with COVID-19 susceptibility and outcomes, including the chr12q24.13 locus encoding antiviral proteins
Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma
J Immunol. 2014 Nov 15;193(10):4783-4789. doi: 10.4049/jimmunol.1302947. Epub 2014 Oct 15. ABSTRACT Allergic asthma is a complex disease with a strong genetic component where mast
COMPARATIVE EFFECTIVENESS OF OMALIZUMAB, MEPOLIZUMAB, AND DUPILUMAB IN ASTHMA: A TARGET TRIAL EMULATION
J Allergy Clin Immunol. 2023 Feb 3:S0091-6749(23)00144-6. doi: 10.1016/j.jaci.2023.01.020. Online ahead of print. ABSTRACT BACKGROUND: Multiple monoclonal antibodies are currently approved for the treatment of