Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-exacerbated Respiratory Disease. A Prospective Trial
Am J Respir Crit Care Med. 2019 Sep 15;200(6):704-711. doi: 10.1164/rccm.201809-1755OC. ABSTRACT Rationale: Daily high-dose aspirin therapy benefits many patients with aspirin-exacerbated respiratory disease but
Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation
J Immunol. 2013 Jun 15;190(12):5927-38. doi: 10.4049/jimmunol.1203202. Epub 2013 May 6. ABSTRACT We reported that Pla2g5-null mice lacking group V secretory phospholipase A2 (gV-sPLA2) showed
Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma
J Immunol. 2014 Nov 15;193(10):4783-4789. doi: 10.4049/jimmunol.1302947. Epub 2014 Oct 15. ABSTRACT Allergic asthma is a complex disease with a strong genetic component where mast
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,
Aspirin/NSAID hypersensitivity evaluations in pregnancy: a case series of initiating low-dose aspirin
Ann Allergy Asthma Immunol. 2024 Oct 7:S1081-1206(24)01569-2. doi: 10.1016/j.anai.2024.10.010. Online ahead of print. NO ABSTRACT PMID:39383942 | DOI:10.1016/j.anai.2024.10.010
A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines
Nat Immunol. 2026 May 22. doi: 10.1038/s41590-026-02517-3. Online ahead of print. ABSTRACT The activation of pattern recognition receptors (PRRs) orchestrates inflammation and regulates adaptive immunity.