Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets
Nat Immunol. 2015 Mar;16(3):306-17. doi: 10.1038/ni.3094. Epub 2015 Jan 26. ABSTRACT The recognized diversity of innate lymphoid cells (ILCs) is rapidly expanding. Three ILC classes
Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity
J Immunol. 2018 Feb 1;200(3):915-927. doi: 10.4049/jimmunol.1700603. Epub 2017 Dec 27. ABSTRACT Cysteinyl leukotrienes (cysLTs) facilitate mucosal type 2 immunopathology by incompletely understood mechanisms. Aspirin-exacerbated
Affinity war: forging immunoglobulin repertoires
Curr Opin Immunol. 2019 Apr;57:32-39. doi: 10.1016/j.coi.2018.12.002. Epub 2019 Jan 25. ABSTRACT B cell immunoglobulin (Ig) repertoire composition shapes immune responses. The generation of Ig
Antibodies induced by ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1
Sci Immunol. 2022 May 10:eabo3425. doi: 10.1126/sciimmunol.abo3425. Online ahead of print. ABSTRACT Neutralizing antibodies that recognize the SARS-CoV-2 spike glycoprotein are the principal host defense
Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation
J Immunol. 2010 May 1;184(9):5325-32. doi: 10.4049/jimmunol.1000104. Epub 2010 Apr 2. ABSTRACT We generated Fas-activated serine threonine phosphoprotein (FAST)-deficient mice (FAST(-/-)) to study the in
Airway brush cells generate cysteinyl leukotrienes through the ATP sensor P2Y2
Sci Immunol. 2020 Jan 17;5(43):eaax7224. doi: 10.1126/sciimmunol.aax7224. Epub 2020 Jan 17. ABSTRACT Chemosensory epithelial cells (EpCs) are specialized cells that promote innate type 2 immunity