Multi-omic analysis reveals a key BCAT1 role in mTOR activation by B-cell receptor and TLR9
J Clin Invest. 2025 Sep 9:e186258. doi: 10.1172/JCI186258. Online ahead of print. ABSTRACT B-lymphocytes play major adaptive immune roles, producing antibody and driving T-cell responses.
Effect of School Integrated Pest Management or Classroom Air Filter Purifiers on Asthma Symptoms in Students With Active Asthma: A Randomized Clinical Trial
JAMA. 2021 Sep 7;326(9):839-850. doi: 10.1001/jama.2021.11559. ABSTRACT IMPORTANCE: School and classroom allergens and particles are associated with asthma morbidity, but the benefit of environmental remediation
Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity
J Exp Med. 2024 Oct 7;221(10):e20231193. doi: 10.1084/jem.20231193. Epub 2024 Sep 25. ABSTRACT Upon antigenic stimulation, naïve CD4+ T cells can give rise to phenotypically
Efficacy and safety of dupilumab in patients with uncontrolled severe CRSwNP and a clinical diagnosis of NSAID-ERD: Results from two randomized placebo-controlled phase 3 trials
Allergy. 2021 Aug 30. doi: 10.1111/all.15067. Online ahead of print. ABSTRACT BACKGROUND: About one-tenth of patients with difficult-to-treat chronic rhinosinusitis with nasal polyps (CRSwNP) have
Clinical phenotypes of immediate first dose reactions to mRNA COVID-19: A multi-center latent class analysis
J Allergy Clin Immunol Pract. 2022 Sep 12:S2213-2198(22)00934-5. doi: 10.1016/j.jaip.2022.08.048. Online ahead of print. ABSTRACT BACKGROUND: Although immediate potentially allergic reactions have been reported after
Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation
Sci Immunol. 2021 Dec 24;6(66):eabj0474. doi: 10.1126/sciimmunol.abj0474. Epub 2021 Dec 24. ABSTRACT [Figure: see text]. PMID:34932383 | DOI:10.1126/sciimmunol.abj0474