Structural and functional impact by SARS-CoV-2 Omicron spike mutations
Cell Rep. 2022 Apr 26;39(4):110729. doi: 10.1016/j.celrep.2022.110729. Epub 2022 Apr 11. ABSTRACT The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), bearing an
IL-4 acts on skin derived dendritic cells to promote the Th2 response to cutaneous sensitization and the development of allergic skin inflammation
J Allergy Clin Immunol. 2024 Jul 10:S0091-6749(24)00682-1. doi: 10.1016/j.jaci.2024.06.021. Online ahead of print. ABSTRACT BACKGROUND: Atopic dermatitis is characterized by scratching and a Th2-dominated local
Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation
Sci Immunol. 2021 Dec 24;6(66):eabj0474. doi: 10.1126/sciimmunol.abj0474. Epub 2021 Dec 24. ABSTRACT [Figure: see text]. PMID:34932383 | DOI:10.1126/sciimmunol.abj0474
Affinity Maturation and Light-Chain-Mediated Paratope Diversification Anticipate Viral Evolution
bioRxiv [Preprint]. 2025 Aug 28:2025.08.27.672735. doi: 10.1101/2025.08.27.672735. ABSTRACT A key goal of vaccinology is to train the immune system to combat current pathogens while simultaneously
Aspirin/NSAID hypersensitivity evaluations in pregnancy: a case series of initiating low-dose aspirin
Ann Allergy Asthma Immunol. 2024 Oct 7:S1081-1206(24)01569-2. doi: 10.1016/j.anai.2024.10.010. Online ahead of print. NO ABSTRACT PMID:39383942 | DOI:10.1016/j.anai.2024.10.010
Allergic inflammatory memory in human respiratory epithelial progenitor cells
Nature. 2018 Aug;560(7720):649-654. doi: 10.1038/s41586-018-0449-8. Epub 2018 Aug 22. ABSTRACT Barrier tissue dysfunction is a fundamental feature of chronic human inflammatory diseases1. Specialized subsets of