Structural and functional characteristics of SARS-CoV-2 Omicron subvariant BA.2 spike
bioRxiv. 2022 Apr 28:2022.04.28.489772. doi: 10.1101/2022.04.28.489772. Preprint. ABSTRACT The Omicron subvariant BA.2 has become the dominant circulating strain of severe acute respiratory syndrome coronavirus 2
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
Affinity Maturation and Light-Chain-Mediated Paratope Diversification Anticipate Viral Evolution
bioRxiv [Preprint]. 2025 Aug 28:2025.08.27.672735. doi: 10.1101/2025.08.27.672735. ABSTRACT A key goal of vaccinology is to train the immune system to combat current pathogens while simultaneously
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
Cell. 2022 Feb 2:S0092-8674(22)00067-8. doi: 10.1016/j.cell.2022.01.009. Online ahead of print. ABSTRACT Activation of the innate immune system via pattern recognition receptors (PRRs) is key to
KVD900, an oral on-demand treatment for hereditary angioedema: Phase 1 study results
J Allergy Clin Immunol. 2022 Jun;149(6):2034-2042. doi: 10.1016/j.jaci.2021.10.038. Epub 2022 Jan 24. ABSTRACT BACKGROUND: Attacks of hereditary angioedema are attributed to excessive plasma kallikrein (PKa)
Cross-reactivity and tolerability of celecoxib in adult patients with NSAID hypersensitivity
J Allergy Clin Immunol Pract. 2019 Nov-Dec;7(8):2891-2893.e4. doi: 10.1016/j.jaip.2019.04.042. Epub 2019 May 14. NO ABSTRACT PMID:31100553 | PMC:PMC7328117 | DOI:10.1016/j.jaip.2019.04.042