KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma
N Engl J Med. 2017 May 18;376(20):1911-1920. doi: 10.1056/NEJMoa1613125. ABSTRACT BACKGROUND: Mast cells are present in the airways of patients who have severe asthma despite
Mast Cells in Lung Damage of COVID-19 Autopsies: a descriptive study
Allergy. 2022 Mar 27. doi: 10.1111/all.15293. Online ahead of print. NO ABSTRACT PMID:35340030 | DOI:10.1111/all.15293
Delayed Large Local Reactions to mRNA-1273 Vaccine against SARS-CoV-2
N Engl J Med. 2021 Apr 1;384(13):1273-1277. doi: 10.1056/NEJMc2102131. Epub 2021 Mar 3. NO ABSTRACT PMID:33657292 | PMC:PMC7944952 | DOI:10.1056/NEJMc2102131
Sequential class switching generates antigen-specific gut IgA from IgG1 B cells
Immunity. 2025 Nov 17:S1074-7613(25)00476-5. doi: 10.1016/j.immuni.2025.10.022. Online ahead of print. ABSTRACT Immunoglobulin (Ig)A is the primary isotype protecting the gut barrier, yet fundamental aspects of
Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation
J Immunol. 2013 Jun 15;190(12):5927-38. doi: 10.4049/jimmunol.1203202. Epub 2013 May 6. ABSTRACT We reported that Pla2g5-null mice lacking group V secretory phospholipase A2 (gV-sPLA2) showed
B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake
J Immunol. 2014 Jul 15;193(2):529-39. doi: 10.4049/jimmunol.1303247. Epub 2014 Jun 13. ABSTRACT Papain, a cysteine protease allergen with inherent adjuvant activity, induces potent IL-4 expression