Expression profiling of constitutive mast cells reveals a unique identity within the immune system
Nat Immunol. 2016 Jul;17(7):878-87. doi: 10.1038/ni.3445. Epub 2016 May 2. ABSTRACT Mast cells are evolutionarily ancient sentinel cells. Like basophils, mast cells express the high-affinity
Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation
Sci Immunol. 2021 Dec 24;6(66):eabj0474. doi: 10.1126/sciimmunol.abj0474. Epub 2021 Dec 24. ABSTRACT [Figure: see text]. PMID:34932383 | DOI:10.1126/sciimmunol.abj0474
COMPARATIVE EFFECTIVENESS OF OMALIZUMAB, MEPOLIZUMAB, AND DUPILUMAB IN ASTHMA: A TARGET TRIAL EMULATION
J Allergy Clin Immunol. 2023 Feb 3:S0091-6749(23)00144-6. doi: 10.1016/j.jaci.2023.01.020. Online ahead of print. ABSTRACT BACKGROUND: Multiple monoclonal antibodies are currently approved for the treatment of
Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity
J Exp Med. 2024 Oct 7;221(10):e20231193. doi: 10.1084/jem.20231193. Epub 2024 Sep 25. ABSTRACT Upon antigenic stimulation, naïve CD4+ T cells can give rise to phenotypically
Antibody Repertoire and Autoimmunity
J Allergy Clin Immunol. 2023 Feb 20:S0091-6749(23)00222-1. doi: 10.1016/j.jaci.2023.02.008. Online ahead of print. NO ABSTRACT PMID:36813185 DOI:10.1016/j.jaci.2023.02.008
Affinity war: forging immunoglobulin repertoires
Curr Opin Immunol. 2019 Apr;57:32-39. doi: 10.1016/j.coi.2018.12.002. Epub 2019 Jan 25. ABSTRACT B cell immunoglobulin (Ig) repertoire composition shapes immune responses. The generation of Ig