Antibodies induced by ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1
Sci Immunol. 2022 May 10:eabo3425. doi: 10.1126/sciimmunol.abo3425. Online ahead of print. ABSTRACT Neutralizing antibodies that recognize the SARS-CoV-2 spike glycoprotein are the principal host defense
Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial
JAMA. 2021 Sep 21;326(11):1013-1023. doi: 10.1001/jama.2021.13374. ABSTRACT IMPORTANCE: In patients who require mechanical ventilation for acute hypoxemic respiratory failure, further reduction in tidal volumes, compared
Affinity war: forging immunoglobulin repertoires
Curr Opin Immunol. 2019 Apr;57:32-39. doi: 10.1016/j.coi.2018.12.002. Epub 2019 Jan 25. ABSTRACT B cell immunoglobulin (Ig) repertoire composition shapes immune responses. The generation of Ig
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
Cell. 2020 May 28;181(5):1016-1035.e19. doi: 10.1016/j.cell.2020.04.035. Epub 2020 Apr 27. ABSTRACT There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome
Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation
J Immunol. 2013 Jun 15;190(12):5927-38. doi: 10.4049/jimmunol.1203202. Epub 2013 May 6. ABSTRACT We reported that Pla2g5-null mice lacking group V secretory phospholipase A2 (gV-sPLA2) showed
Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets
Nat Immunol. 2015 Mar;16(3):306-17. doi: 10.1038/ni.3094. Epub 2015 Jan 26. ABSTRACT The recognized diversity of innate lymphoid cells (ILCs) is rapidly expanding. Three ILC classes