Somatic hypermutation unlocks antibody specificities beyond the primary repertoire
Immunity. 2025 May 2:S1074-7613(25)00177-3. doi: 10.1016/j.immuni.2025.04.014. Online ahead of print. ABSTRACT B cell somatic hypermutation (SHM) and selection in germinal centers (GCs) enhance antibody affinity
Association of Self-reported High-Risk Allergy History With Allergy Symptoms After COVID-19 Vaccination
JAMA Netw Open. 2021 Oct 1;4(10):e2131034. doi: 10.1001/jamanetworkopen.2021.31034. ABSTRACT IMPORTANCE: Allergic history in individuals with confirmed anaphylaxis to a messenger RNA (mRNA) COVID-19 vaccine is
The Discovery of Discrete Developmental Pathways Directing Constitutive and Induced Mast Cells in Mice
J Immunol. 2021 Jul 15;207(2):359-361. doi: 10.4049/jimmunol.2100432. NO ABSTRACT PMID:34644258 | DOI:10.4049/jimmunol.2100432
Anion Exchanger 2 Regulates Dectin-1-Dependent Phagocytosis and Killing of Candida albicans
PLoS One. 2016 Jul 8;11(7):e0158893. doi: 10.1371/journal.pone.0158893. eCollection 2016. ABSTRACT Anion exchanger 2 (Ae2; gene symbol, Slc4a2) is a plasma membrane Cl-/HCO3- exchanger expressed in
Immunology of allergen immunotherapy
Immunother Adv. 2022 Nov 25;2(1):ltac022. doi: 10.1093/immadv/ltac022. eCollection 2022. NO ABSTRACT PMID:36530352 | PMC:PMC9749131 | DOI:10.1093/immadv/ltac022
SARS-CoV-2 epitope-specific CD4+ memory T cell responses across COVID-19 disease severity and antibody durability
Sci Immunol. 2022 Apr 21:eabl9464. doi: 10.1126/sciimmunol.abl9464. Online ahead of print. ABSTRACT CD4+ T cells are central to long-term immunity against viruses through the functions