Updating the classification and routine diagnosis of NSAID hypersensitivity reactions: A WAO Statement
World Allergy Organ J. 2025 Aug 12;18(8):101086. doi: 10.1016/j.waojou.2025.101086. eCollection 2025 Aug. ABSTRACT Hypersensitivity reactions to non-steroidal anti-inflammatory drugs (NSAIDs) have been classified as immediate
Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99
Proc Natl Acad Sci U S A. 2016 May 31;113(22):6242-7. doi: 10.1073/pnas.1605957113. Epub 2016 May 16. ABSTRACT Cysteinyl leukotrienes (cysLTs), leukotriene C4 (LTC4), LTD4, and
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
Cell. 2022 Feb 2:S0092-8674(22)00067-8. doi: 10.1016/j.cell.2022.01.009. Online ahead of print. ABSTRACT Activation of the innate immune system via pattern recognition receptors (PRRs) is key to
Chemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells
J Exp Med. 2011 Nov 21;208(12):2511-24. doi: 10.1084/jem.20102545. Epub 2011 Oct 31. ABSTRACT Naive antiviral CD8(+) T cells are activated in the draining LN (DLN)
Global processing provides malignancy evidence complementary to the information captured by humans or machines following detailed mammogram inspection
Sci Rep. 2021 Oct 11;11(1):20122. doi: 10.1038/s41598-021-99582-5. ABSTRACT The information captured by the gist signal, which refers to radiologists’ first impression arising from an initial
Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy
J Clin Immunol. 2021 Oct;41(7):1597-1606. doi: 10.1007/s10875-021-01034-2. Epub 2021 Jun 28. ABSTRACT PURPOSE: Adenosine deaminase (ADA) deficiency causes severe combined immunodeficiency (SCID) through an accumulation