Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,
Secretory phospholipases A2 induce cytokine release from blood and synovial fluid monocytes
Eur J Immunol. 2002 Jan;32(1):67-76. doi: 10.1002/1521-4141(200201)32:13.0.CO;2-3. ABSTRACT Secretory phospholipases A2 (sPLA2) are released in the blood of patients with various inflammatory diseases and exert
Structural and functional characteristics of SARS-CoV-2 Omicron subvariant BA.2 spike
bioRxiv. 2022 Apr 28:2022.04.28.489772. doi: 10.1101/2022.04.28.489772. Preprint. ABSTRACT The Omicron subvariant BA.2 has become the dominant circulating strain of severe acute respiratory syndrome coronavirus 2
High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform
Nat Biotechnol. 2023 Jan 2. doi: 10.1038/s41587-022-01566-x. Online ahead of print. ABSTRACT Identification of CD8+ T cell epitopes is critical for the development of immunotherapeutics.
Omicron’s message on vaccines: Boosting begets breadth
Cell. 2022 Feb 3;185(3):411-413. doi: 10.1016/j.cell.2022.01.006. Epub 2022 Jan 14. ABSTRACT In this issue of Cell, three studies confirm that SARS-CoV-2 Omicron strongly evades a
Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-exacerbated Respiratory Disease. A Prospective Trial
Am J Respir Crit Care Med. 2019 Sep 15;200(6):704-711. doi: 10.1164/rccm.201809-1755OC. ABSTRACT Rationale: Daily high-dose aspirin therapy benefits many patients with aspirin-exacerbated respiratory disease but