Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy
J Clin Immunol. 2021 Oct;41(7):1597-1606. doi: 10.1007/s10875-021-01034-2. Epub 2021 Jun 28. ABSTRACT PURPOSE: Adenosine deaminase (ADA) deficiency causes severe combined immunodeficiency (SCID) through an accumulation
Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection
Cell Rep. 2025 Apr 1;44(4):115472. doi: 10.1016/j.celrep.2025.115472. Online ahead of print. ABSTRACT Memory lymphocytes are durable cells that persist in the absence of antigen, but
Structural and functional characteristics of SARS-CoV-2 Omicron subvariant BA.2 spike
bioRxiv. 2022 Apr 28:2022.04.28.489772. doi: 10.1101/2022.04.28.489772. Preprint. ABSTRACT The Omicron subvariant BA.2 has become the dominant circulating strain of severe acute respiratory syndrome coronavirus 2
Allergic inflammatory memory in human respiratory epithelial progenitor cells
Nature. 2018 Aug;560(7720):649-654. doi: 10.1038/s41586-018-0449-8. Epub 2018 Aug 22. ABSTRACT Barrier tissue dysfunction is a fundamental feature of chronic human inflammatory diseases1. Specialized subsets of
Long-term cognitive and psychiatric outcomes of acute respiratory distress syndrome managed with Extracorporeal Membrane Oxygenation
Respir Med. 2021 Jul;183:106419. doi: 10.1016/j.rmed.2021.106419. Epub 2021 Apr 28. ABSTRACT BACKGROUND: Cognitive dysfunction is often reported in patients who have experienced acute respiratory distress
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
Cell. 2020 May 28;181(5):1016-1035.e19. doi: 10.1016/j.cell.2020.04.035. Epub 2020 Apr 27. ABSTRACT There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome